Li-Fraumeni syndrome

Mutation in TP53 (Li-Fraumeni-Syndrom): gesteigerte Risiko für Sarkome, Tumore der Nebennieren, Leukämien und Hirntumoren (Shulman et all, Hereditary breast and ovarian cancer (HBOC): clinical features and counseling for BRCA1 and BRCA2, Lynch syndrome, Cowden syndrome, and Li-Fraumeni syndrome. Obstetrics and Gynecology Clinics of North America, 2010)